First, it’s important to note that this was back in 2006 and a lot has changed in 15 years. Especially the first part about, “you can’t do all the work yourself.” Sure, back in 2006 I think this was pretty true — in fact, this was the very year that Amazon Web Services was first launched, so cloud computing hadn’t taken off yet.
I think there’s a lot of truth in Paul Graham’s words. Beware of tunnel vision: if your product is a cloud based solution you may be right, but in many other markets you really need more than one brain and one persons skill set to be successful. My own startup is targeting the manufacturing industry – that’s not a market where putting out a web site on AWS will get you anywhere.
For your case, building alone might be good, for me — for us, it isn’t.